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#Biotechnology and Medical Research (TRBC)

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Actelion`s Opsumit drug missed trial endpoint: doctor

Actelion’s Opsumit drug missed a primary endpoint in a late-stage study of patients with pulmonary arterial hypertension due to Eisenmenger Syndrome, a doctor involved in the trial said in a statement from the Swiss drugmaker. More »

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Merck, Bristol-Myers agree to settle Keytruda patent suit

Merck & Co said it agreed to enter into a settlement and license agreement with Bristol-Myers Squibb Co and Ono Pharmaceutical Co Ltd to resolve all global patent-infringement litigation related to its cancer drug, Keytruda. More »

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New drug approvals fall to six-year low in 2016

A person holds pharmaceutical tablets and capsules in this picture illustration taken in Ljubljana September 18, 2013. REUTERS/Srdjan Zivulovic Last year turned out to be a disappointing one for new drug approvals with the U.S. Food and Drug Administration cle... More »

Equity, Macro hedge funds look to bounce back from a tough year

An electoral poster of Donald Trump is displayed on the floor of the New York Stock Exchange (NYSE) the morning after the U.S. presidential election in New York City, U.S., November 9, 2016. REUTERS/Brendan McDermid For some equity funds and those betting on m... More »

Artificial leaf copies nature to manufacture medicine

An artificial leaf designed by scientists at Eindhoven University of Technology, Netherlands December 16, 2016. REUTERS/Jim Drury Dutch scientists have developed an artificial leaf that can act as a mini-factory for producing drugs, an advance that could allow... More »

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New data on risk vs benefit for potent CAR-T cancer drugs

A promising but risky new group of customized cancer drugs will be in focus this weekend at the annual meeting of the American Society of Hematology (ASH), where clinical trial results will help clarify their potential for doctors and investors. More »

U.S. health spending in 2015 rose at fastest rate since 2007

A person holds pharmaceutical tablets and capsules in this picture illustration taken in Ljubljana September 18, 2013. REUTERS/Srdjan Zivulovic U.S. health spending in 2015 rose at its fastest rate since 2007, driven by expanded access to insurance under the A... More »

Czech scientists develop human lung model to aid treatments

Scientist Frantisek Lizal looks at a model of a functioning human lung that can be used to simulate chronic diseases and their treatments in the Brno University of Technology in Brno, Czech Republic, November 22, 2016. Picture taken November 22, 2016. REUTERS/... More »

Actelion confirms Johnson & Johnson approach

A general view shows Swiss biotech group Actelion Headquarters in Allschwil near Basel February 17, 2015. REUTERS/Arnd Wiegmann Actelion (ATLN.S) has confirmed it has been approached by Johnson & Johnson (JNJ.N) about a possible transaction to take over the Sw... More »

Johnson & Johnson approaches Actelion about takeover deal

A general view shows Swiss biotech group Actelion Headquarters in Allschwil near Basel February 17, 2015. REUTERS/Arnd Wiegmann U.S. healthcare company Johnson & Johnson (JNJ.N) said on Friday it was in preliminary talks with Actelion (ATLN.S) about a potentia... More »

Janus portfolio manager sees more biotech gains on Trump

A man uses an umbrella to guard against snowfall as he walks past the Nasdaq MarketSite in Times Square, Midtown New York March 20, 2015. REUTERS/Adrees Latif Biotech stocks still have room to rise after the election of Donald Trump as U.S. president, which re... More »

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Corbus`s lead drug succeeds in mid-stage scleroderma study

Corbus Pharmaceuticals Holdings Inc said its lead drug outperformed a placebo in a mid-stage study involving patients with a form of systemic sclerosis, an incurable autoimmune condition caused by abnormal growth of connective tissue. More »

Dynavax says FDA rejects its hepatitis B vaccine

A view shows the U.S. Food and Drug Administration (FDA) headquarters in Silver Spring, Maryland August 14, 2012. REUTERS/Jason Reed/File Photo Dynavax Technologies Corp said on Monday the U.S. Food and Drug Administration had rejected the marketing applicatio... More »

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Stanford uses CRISPR to correct sickle cell, human trials planned

Scientists at Stanford University School of Medicine have used the CRISPR gene editing tool to repair the gene that causes sickle cell disease in stem cells from diseased patients, paving the way for a potential cure for the disease, which affects up to 5 mill... More »

Sanders urges Californians to approve drug price ballot measure

U.S. Democratic presidential nominee Hillary Clinton listens as U.S. Senator Bernie Sanders speaks about college affordability during a campaign event at the University of New Hampshire in Durham, New Hampshire, United States September 28, 2016. REUTERS/Brian ... More »

Trio wins Nobel chemistry prize for `world`s smallest machines`

J. Fraser Stoddart, one of the winners of 2016 Nobel Prize for Chemistry, raises his glass for a toast at Northwestern University in the Chicago suburb of Evanston, Illinois, U.S., October 5, 2016. REUTERS/Jim Young A trio of European scientists has won the 20... More »

Medtech startup teams with GM on robotic glove for assembly lines

The GM logo is seen in Warren, Michigan, U.S. on October 26, 2015. REUTERS/Rebecca Cook/File Photo Bioservo Technologies, a medical technology firm that makes a light-weight robotic “extra muscle” glove for people with weak grips is teaming up with carmaker Ge... More »

Big Pharma vs Big Pharma in court battles over biosimilar drugs

An Amgen sign is seen at the company’s office in South San Francisco, California in this October 21, 2013 file photo. REUTERS/Robert Galbraith/Files The line dividing makers of brand-name drugs and copycat medicines is blurring as companies known for innovativ... More »

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Endo International CEO steps down, Campanelli named successor

Endo International Plc (ENDP.O) said Chief Executive Rajiv De Silva had stepped down and would be replaced by generics division head Paul Campanelli, as the drugmaker grapples with a large debt load and mounting pressure on some of its drug prices. More »

Sanofi may win U.S. approval of $3 billion eczema drug by March

French multinational pharmaceutical company SANOFI logo is seen at the headquarters in Paris, France, March 8, 2016. REUTERS/Philippe Wojazer/File Photo French drugmaker Sanofi (SASY.PA) and its U.S. partner Regeneron Pharmaceuticals (REGN.O) could win U.S. ap... More »

Pfizer says not to split into two

The Pfizer logo is seen at their world headquarters in Manhattan, New York, U.S., August 1, 2016. REUTERS/Andrew Kelly U.S. drugmaker Pfizer Inc said on Monday it had decided not to separate into two publicly traded companies at this time. More »

Valeant says discount program for heart drugs on track

A sign for the headquarters of Valeant Pharmaceuticals International Inc is seen in Laval, Quebec June 14, 2016. REUTERS/Christinne Muschi Valeant Pharmaceuticals International Inc said its discount and rebates program for two high-priced heart drugs would cov... More »

Sanofi, Google parent in $500 million diabetes joint venture

A logo is seen in front of the entrance at the headquarters French drugmaker Sanofi in Paris October 30, 2014. REUTERS/Christian Hartmann/File Photo French drugmaker Sanofi and Google owner Alphabet’s life sciences firm Verily are to invest about $500 million ... More »

Tiny `fitbits` to keep tabs on the body from within

A dust-sized wireless sensor that makes it possible to wirelessly monitor neural activity in real time when implanted inside the body, is shown on a finger in this handout photo. UC Berkeley/Handout via Reuters Scientists are developing dust-sized wireless sen... More »

U.S. rate hike fears weigh on fund flows in latest week

Traders work on the floor of the New York Stock Exchange (NYSE) shortly after the opening bell in New York, U.S., August 30, 2016. REUTERS/Lucas Jackson The party looked to be waning for some popular investments in the latest week, with investors trimming expo... More »

FDA recommends Zika testing for all blood donated in U.S.

An edes aegypti mosquito is seen inside a test tube as part of a research on preventing the spread of the Zika virus and other mosquito-borne diseases at a control and prevention center in Guadalupe, neighbouring Monterrey, Mexico, March 8, 2016. REUTERS/Danie... More »

Valeant under criminal investigation over Philidor ties: WSJ

NEW YORK/SAN FRANCISCO U.S. prosecutors have opened a criminal investigation into Valeant Pharmaceuticals International Inc (VRX.N) over whether it hid from insurers its relationship with a specialty pharmacy that helped boost its drug sales, the Wall Street J... More »

Clinton urges U.S. Congress to reconvene, pass Zika bill

MIAMI U.S. Democratic presidential candidate Hillary Clinton urged federal lawmakers currently on summer recess back into session to pass a crucial funding bill to combat the Zika virus as she visited a health clinic at the heart of a local outbreak in Miami o... More »

Healthy clones: Dolly the sheep’s heirs reach ripe old age

LONDON The heirs of Dolly the sheep are enjoying a healthy old age, proving cloned animals can live normal lives and offering reassurance to scientists hoping to use cloned cells in medicine. Dolly, cloning’s poster child, was born in Scotland in 1996. She die... More »

For the first time, scientists to sequence genes in space

CAPE CANAVERAL, Fla/CHICAGO Given her background in researching some of the deadliest pathogens on Earth, including Ebola, colleagues of newly arrived astronaut Kate Rubins had expected her to want to do “crazy science fiction” on the International Space Stati... More »

Regulator says too many drugmakers chasing same cancer strategy

CHICAGO A new type of cancer drug that takes the brakes off the body’s immune system has given drugmakers some remarkable wins against the deadly disease, but a top U.S. regulator says too many companies are focused on the same approach. Dr. Richard Pazdur, he... More »

FDA staff posts voting questions for Teva’s opioid painkiller

U.S. Food and Drug Administration staff released voting questions on Teva Pharmaceutical Industries Ltd’s long-acting opioid painkiller for a panel of independent experts who will recommend to the agency whether to approve the drug. An FDA spokesman on Friday ... More »

Teva’s opioid not abuse-deterrent when taken orally: FDA staff

An experimental, long-acting painkiller made by Teva Pharmaceutical Industries Ltd does not have abuse-resistant properties when taken orally, according to a preliminary review by the U.S. Food and Drug Administration. The drug, whose proposed trade name is Va... More »

Scientists propose project to build synthetic human genome

WASHINGTON A group of 25 scientists on Thursday proposed an ambitious project to create a synthetic human genome, or genetic blueprint, in an endeavor that is bound to raise concerns over the extent to which human life can or should be engineered. A synthetic ... More »

Valeant to provide rebate programs for two heart drugs

Valeant Pharmaceuticals International Inc said on Monday it would make available to all hospitals in the United States an enhanced rebate program to reduce the price of its heart drugs Nitropress and Isuprel. All hospitals are eligible for a rebate of at least... More »

Futures little changed after bruising week

U.S. stock index futures were little changed on Monday following a bruising week that left the Dow and the S&P 500 lower for the third straight week. * U.S. stocks fell on Friday as a decline in oil prices added to pressure from consumer companies after gloomy... More »

Dan Loeb’s Third Point adds 700,000 shares of Alphabet: filing

NEW YORK Dan Loeb’s hedge fund Third Point LLC bought more than a half a million Class A share position of Google parent Alphabet Inc, according to a Securities and Exchange Commission filing late Friday. Third Point took a new stake of 700,000 Alphabet shares... More »

Teens most drawn to e-cigarettes by online ads

(Reuters Health) – While many forms of e-cigarette advertising increase the odds that teens will try the devices, a new U.S. study suggests that this generation of digital natives is most enticed by promotions they see online. Big U.S. tobacco companies are al... More »

AstraZeneca taps gene pioneer Venter for huge drug-hunting sweep

CAMBRIDGE, England AstraZeneca, working with genome pioneer Craig Venter, is launching a massive gene hunt in the most comprehensive bet yet by a pharmaceutical firm on the potential of genetic variations to unlock routes to new medicines. The initiative, anno... More »

New AbbVie hepatitis C regimen shows high cure rates: studies

An experimental once-daily combination hepatitis C treatment being developed by AbbVie Inc demonstrated very high cure rates across a wide range of disease genotypes, according to data presented on Saturday, likely giving the company a more competitive product... More »

Device harnessing thoughts allows quadriplegic to use his hands

WASHINGTON An Ohio man paralyzed in an accident while diving in waves can now pick up a bottle or play the video game Guitar Hero thanks to a small computer chip in his brain that lets his mind guide his hands and fingers, bypassing his damaged spinal cord. Sc... More »

Samsung brings in the lawyers for biosimilars push

SEOUL Samsung Bioepis Co Ltd, which aims to become a force in the fledgling biosimilar drugs industry, has filed a lawsuit against the originator of the world’s best-selling drug, to stop it blocking the launch of its own version. The unit of South Korea’s Sam... More »

Europe gives green light to first gene therapy for children

LONDON The world’s first life-saving gene therapy for children, developed by Italian scientists and GlaxoSmithKline, has been recommended for approval in Europe, boosting the pioneering technology to fix faulty genes. The European Medicines Agency (EMA) said o... More »

U.S. firms target investment in Israeli cannabis R&D

TEL AVIV Already a pioneer in high-tech and cutting-edge agriculture, Israel is starting to attract American companies looking to bring medical marijuana know-how to a booming market back home. Since 2014, U.S. firms have invested about $50 million in licensin... More »

Sanofi poaches AstraZeneca scientist as new research head

LONDON French drugmaker Sanofi has poached one of AstraZeneca’s top scientists to be its new research head in another high-profile departure for the British drugmaker. Sanofi said on Tuesday that Yong-Jun Liu had been appointed as head of research with effect ... More »

Stripped-down synthetic organism sheds light on nature of life

WASHINGTON Scientists on Thursday announced the creation of a synthetic organism stripped down to the bare essentials with the fewest genes needed to survive and multiply, a feat at the microscopic level that may provide big insights on the very nature of life... More »

Better inhaler lessons can prevent asthma emergencies

Reuters Health – A major weakness of asthma care is that many patients don’t know how to use inhalers to deliver life-saving medicine when they’re gasping for air. The fix may be as simple as taking more time to teach patients how the devices work, a U.S. stud... More »

FDA says engineered anti-Zika mosquito environmentally safe

U.S. health regulators said a genetically engineered mosquito being used in the fight against Zika will not have a significant impact on the environment, possibly paving the way for the technique to be used in the country. The self-limiting strain of the Aedes... More »

CDC cautions pregnant women against travel to Rio Olympics

Pregnant women should consider not traveling to the 2016 Olympic Games in Brazil due to the risk of Zika virus infection, the U.S. Centers for Disease Control and Prevention said on Friday. CDC also said women considering becoming pregnant, and their male part... More »

Zika may have been sexually transmitted in 14 cases: CDC

U.S. health officials are investigating 14 reports of the Zika virus that may been transmitted through sex, including to several pregnant women, raising new questions about the role sexual transmission is playing in the growing outbreak. In two of the suspecte... More »

French drug trial volunteer dies: hospital

RENNES, France A man left brain dead after a drug trial in northwest France died on Sunday, said the hospital where he was being treated. The Rennes hospital said in a statement that five other volunteers were in stable condition after they were admitted last ... More »