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Opioid settlement talks fail, landmark trial expected Monday

CLEVELAND (Reuters) – A landmark trial over the U.S. opioid epidemic is on track to begin on Monday after drug companies and local governments failed to agree on a settlement on Friday that had been expected to be valued at around $50 billion. Top executives o... More »

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J&J liable for $572 million in Oklahoma opioid epidemic trial-…

NORMAN, Okla./BOSTON (Reuters) – An Oklahoma judge on Monday ordered Johnson & Johnson (JNJ.N) to pay $572.1 million to the state for its part in fueling an opioid epidemic by deceptively marketing addictive painkillers, a sum that was substantially less than ... More »

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Factbox: Oklahoma judge finds J&J liable in first trial over opioids

(Reuters) – An Oklahoma judge on Monday ruled that Johnson & Johnson (JNJ.N) was liable for its part in fueling the opioid epidemic and ordered the drugmaker to pay $572 million following a trial in a lawsuit brought by the state’s attorney general. J&J said i... More »

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Oklahoma, J&J to wrap up first trial over opioid crisis

(Reuters) – Oklahoma’s attorney general is expected on Monday to urge a judge to find Johnson & Johnson responsible for flooding the market with painkillers and fueling the U.S. opioid epidemic, as the first trial in nationwide litigation over the drug crisis ... More »

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Teva Pharm to pay Oklahoma $85 million to settle opioid claims

BOSTON/JERUSALEM (Reuters) – Teva Pharmaceutical Industries Ltd said on Sunday it had agreed to pay an $85 million settlement with the state of Oklahoma days before the company was set to face trial over allegations that it and other drugmakers helped fuel the... More »

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Israeli firm gets U.S. nod for advanced trials for non-opiate…

JERUSALEM (Reuters) – Israeli pharmaceuticals company PainReform has received approval from the U.S. Food and Drug Administration (FDA) to begin late-stage clinical studies for a pain relief drug that is a departure from opiate-based narcotics, it said on Tues... More »

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U.S. agency rescinds order banning Louisiana distributor from…

WASHINGTON (Reuters) – The U.S. Drug Enforcement Administration on Friday reversed an order that halted a Louisiana drug wholesaler’s opioid sales over allegations it failed to report suspiciously large orders by pharmacies for the narcotics, court documents s... More »

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U.S. joins whistleblower case against Insys over kickbacks

(Reuters) – The U.S. Department of Justice has joined whistleblower litigation accusing Insys Therapeutics Inc of trying to generate more profit by paying kickbacks to doctors to prescribe powerful opioid medications. The government’s involvement was disclosed... More »

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U.S. drug agency suspends Louisiana distributor over opioid sales

WASHINGTON (Reuters) – The U.S. Drug Enforcement Administration said on Friday it had suspended a Louisiana pharmaceutical distributor from selling controlled substances for allegedly selling unusually large quantities of opioids to pharmacies without reportin... More »

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Arkansas sues opioid manufacturers for roles in epidemic

(Reuters) – Arkansas’ attorney general on Thursday joined the widening mass of litigation against opioid manufacturers, accusing three drugmakers of promoting addictive painkillers in ways that falsely denied or trivialized their risks. Arkansas Attorney Gener... More »

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New York accuses Insys of deceptively marketing opioid

FILE PHOTO: A box of the Fentanyl-based drug Subsys, made by Insys Therapeutics Inc, appears in an undated photograph provided by the U.S. Attorney’s Office for the Southern District of Alabama. U.S. Attorney’s Office for the Southern District of Alabama/Hando... More »

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Delaware sues opioid manufacturers, distributors over epidemic

FILE PHOTO: A pharmacist holds prescription painkiller OxyContin, 40mg pills, made by Purdue Pharma L.D. at a local pharmacy, in Provo, Utah, U.S. on April 25, 2017. REUTERS/George Frey/File Photo (Reuters) – Delaware on Friday became the latest state to file ... More »

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Boston-area paramedics on front lines of U.S. opioid crisis

Cataldo Ambulance medics John Gardner (L) and David Farmer care for a man in his 40’s who was found unresponsive after overdosing on an opioid in the Boston suburb of Salem, Massachusetts, U.S., August 9, 2017. REUTERS/Brian Snyder (Reuters) – The paramedics f... More »

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Indivior drug to fight opioid addiction approved by U.S. FDA

(Reuters) – Indivior’s experimental drug to help fight America’s growing opioid addiction crisis was approved by the U.S. Food and Drug Administration late on Thursday, boosting its sales prospects as competitors threaten revenues from an older product. Shares... More »

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U.S. drug agency to toughen stance on illicit fentanyl analogues

The U.S. Drug Enforcement Administration said on Thursday that it would classify illicit versions of the synthetic opioid fentanyl at the same level as heroin, allowing criminal prosecution of anyone who possesses, distributes or manufactures illicit versions ... More »

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Billionaire Insys founder charged in U.S. opioid bribe case

The billionaire founder of Insys Therapeutics Inc was arrested on Thursday on U.S. charges he participated in a scheme to bribe doctors to prescribe a fentanyl-based cancer pain drug, marking a step by authorities to fight the opioid epidemic. More »

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Trump declares opioids a U.S. public health emergency

U.S. President Donald Trump declared the opioid crisis a public health emergency on Thursday, stopping short of a national emergency declaration he promised months ago that would have freed up more federal money. More »

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Makers of fast-acting opioids will have to pay for training: FDA

Makers of fast-acting opioids will have to fund voluntary training for healthcare professionals who prescribe the drugs, including education on safe prescribing practices and non-opioid alternatives, the U.S. Food and Drug Administration (FDA) said on Thursday... More »

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Washington state sues OxyContin maker Purdue Pharma

Washington state on Thursday sued OxyContin maker Purdue Pharma LP, becoming the latest state or local government to file a lawsuit seeking to hold pharmaceutical companies accountable for a national opioid addiction epidemic. More »

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New Mexico sues opioid drug manufacturers, distributors

New Mexico on Thursday sued eight opioid manufacturers and wholesale distributors, becoming the latest state or local government to file a lawsuit seeking to hold corporations accountable for a national drug addiction epidemic. More »

Obama signs into law opioid addiction bill to protect newborns

WASHINGTON President Barack Obama on Friday signed into law a measure that pledges greater efforts to protect drug-dependent newborns and assist their parents. The Comprehensive Addiction and Recovery Act also stresses drug treatment and overdose prevention to... More »

Teva’s opioid not abuse-deterrent when taken orally: FDA staff

An experimental, long-acting painkiller made by Teva Pharmaceutical Industries Ltd does not have abuse-resistant properties when taken orally, according to a preliminary review by the U.S. Food and Drug Administration. The drug, whose proposed trade name is Va... More »