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Opioid settlement talks fail, landmark trial expected Monday

CLEVELAND (Reuters) – A landmark trial over the U.S. opioid epidemic is on track to begin on Monday after drug companies and local governments failed to agree on a settlement on Friday that had been expected to be valued at around $50 billion. Top executives o... More »

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Virtual reality helps kids getting X-rays

(Reuters Health) – A virtual reality program with cartoon characters may reduce children’s fear before imaging procedures, a South Korean study suggests. Compared to verbal instructions, a virtual reality experience that explained the process of chest X-rays i... More »

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Most kids can manage pain after surgery without opioids

(Reuters Health) – About one in five kids are prescribed opioids after common pediatric surgeries, but a new study suggests they may do just as well with alternative pain relievers like acetaminophen or ibuprofen. From 1999 to 2016, opioid-related overdoses ro... More »

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J&J liable for $572 million in Oklahoma opioid epidemic trial-…

NORMAN, Okla./BOSTON (Reuters) – An Oklahoma judge on Monday ordered Johnson & Johnson (JNJ.N) to pay $572.1 million to the state for its part in fueling an opioid epidemic by deceptively marketing addictive painkillers, a sum that was substantially less than ... More »

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Oklahoma, J&J to wrap up first trial over opioid crisis

(Reuters) – Oklahoma’s attorney general is expected on Monday to urge a judge to find Johnson & Johnson responsible for flooding the market with painkillers and fueling the U.S. opioid epidemic, as the first trial in nationwide litigation over the drug crisis ... More »

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Common nerve pain drug linked to suicidal behavior, overdose

(Reuters Health) – A class of medications used for nerve and muscle pain, including the popular drug Lyrica, increases users’ risks for suicidal behavior, unintentional overdoses, injuries and car accidents – and the risks are particularly high for teens and y... More »

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Teva Pharm to pay Oklahoma $85 million to settle opioid claims

BOSTON/JERUSALEM (Reuters) – Teva Pharmaceutical Industries Ltd said on Sunday it had agreed to pay an $85 million settlement with the state of Oklahoma days before the company was set to face trial over allegations that it and other drugmakers helped fuel the... More »

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Expert panel advises against surgery for shoulder pain

(Reuters Health) – Surgery for shoulder pain that isn’t caused by an injury has no better results than nonsurgical options or placebo surgery, and comes with potential harms, an expert panel has concluded. The international panel of clinicians, researchers and... More »

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Hospitals serving more minorities may offer less palliative care

(Reuters Health) – Patients may have less access to palliative care at U.S. hospitals that primarily serve minorities, a study suggests. Minorities in the U.S. often receive worse healthcare and have worse outcomes, researchers note in JAMA Network Open. Non-w... More »

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Patients need practical surgical recovery advice

(Reuters Health) – Patients undergoing surgery don’t often receive practical advice about what to do and what to expect during the recovery process, says a surgeon who has been on the giving and receiving end of post-op instructions. These directions need a mo... More »

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Giving birth in water appears safe for mother and infant

(Reuters Health) – Giving birth in water, also known as immersion labor and delivery or waterbirth, appears safe for mother and baby, at least when it takes place in a hospital. Increasing numbers of women choose to labor and give birth in water, particularly ... More »

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Fiery pepper causes ‘thunderclap’ headache

(Reuters Health) – Eating super-hot chili peppers can have painful effects that extend beyond a blazing mouth, doctors warn. After downing a “Carolina Reaper,” billed as the world’s hottest chili pepper at the time, a 34-year-old man developed intense head and... More »

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Flexion`s knee pain drug gets FDA nod, shares hit life high

Flexion Therapeutics Inc said its injectable drug to treat osteoarthritis-related knee pain was approved by the U.S. Food and Drug Administration, sending the drug developer's shares soaring to a record high in regular trading on Friday. More »

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Endo pulls opioid as U.S. seeks to tackle abuse epidemic

Endo International Plc said on Thursday it agreed to withdraw its long-acting opioid painkiller Opana ER from the market after the U.S. Food and Drug Administration declared its benefit did not outweigh public health risks associated with opioid abuse. More »

Teva’s opioid not abuse-deterrent when taken orally: FDA staff

An experimental, long-acting painkiller made by Teva Pharmaceutical Industries Ltd does not have abuse-resistant properties when taken orally, according to a preliminary review by the U.S. Food and Drug Administration. The drug, whose proposed trade name is Va... More »

FDA staff posts voting questions for Teva’s opioid painkiller

U.S. Food and Drug Administration staff released voting questions on Teva Pharmaceutical Industries Ltd’s long-acting opioid painkiller for a panel of independent experts who will recommend to the agency whether to approve the drug. An FDA spokesman on Friday ... More »

Exercise eases knee osteoarthritis, temporarily

(Reuters Health) – A therapeutic program of weight-bearing exercise reduces pain and improves joint function, at least for two to six months, for people with osteoarthritis, according to a review of previous trials. “We had a systematic review for Cochrane fro... More »

Scientists crack gene secret that lets poppies make morphine

LONDON Scientists have identified a key gene used by poppies to make morphine, paving the way for better methods of producing the medically important drug, potentially without the need for cultivating poppy fields. The latest finding follows recent success in ... More »